10 Weirdest Medical Conditions


1. Epidermodysplasia Verruciformis

Epidermodysplasia Verruciformis
Epidermodysplasia verruciformis (also called Lewandowsky-Lutz dysplasia or Lutz-Lewandowsky epidermodysplasia verruciformis) is an extremely rare autosomal recessive genetic hereditary skin disorder associated with a high risk of carcinoma of the skin. It is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin. The people resemble bark of trees .


2. Progeria

Progeria (also known as “Hutchinson–Gilford progeria syndrome” and “Hutchinson–Gilford syndrome”) is an extremely rare, severe, genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The disorder has a very low incidence and occurs in one per eight million live births. Those born with progeria typically live about thirteen years, although many have been known to live into their late teens and early twenties and rare individuals may even reach their forties. It is a genetic condition that occurs as a new mutation and is not usually inherited, although there is a uniquely inheritable form. This is in contrast to another rare but similar premature aging syndrome, dyskeratosis congenita (DKC), which is inheritable and will often be expressed multiple times in a family line.

It caused by a single gene affect in child’s genetic code resulting in hastening of normal aging process thus causing premature aging.


3. Aquagenic Urticaria

Aquagenic Urticaria
Aquagenic urticaria, also known as water allergy, the sufferer can’t go from a nice hot water bath or a shower or enjoy swimming, even sweating after a tiresome work brings a painful rash, it is an extremely rare form of physical urticaria. It is sometimes described as an allergy, although it is not a histamine releasing allergic reaction like other forms of urticaria; it is more a hypersensitivity to the ions found in non-distilled water. In affected persons, water on the skin causes hives to appear within 15 minutes and last for up to two hours. It is very unusual.


4. Alice in The Wonderland Syndrome (AIWS) Or Todd’s Syndrome:

Alice in The Wonderland Syndrome
Alice in Wonderland syndrome, also known as Todd’s syndrome, is a disorienting neurological condition which affects human perception. Sufferers may experience micropsia, macropsia, and/or size distortion of other sensory modalities. A temporary condition, it is often associated with migraines, brain tumors, and the use of psychoactive drugs

Micropsia is a neurological condition affecting human visual perception in which humans, inanimate and animate objects are perceived to be substantially smaller than they actually are. Micropsia can be caused by either optical distortion of images in the eye (as by glasses or certain ocular conditions) or by a neurological dysfunction. Similarly  macropsia is the reverse condition characterized by objects appearing substantially larger than they actually are e.g a car may seem as big as a mountain.


5. Arnold Chiari Malformation

Arnold Chiari Malformation
Arnold-Chiari malformation is a malformation of the brain. It consists of a downward displacement of the brain into the spinal cord. This boy Rhett Lamb is not oridinary in the fact he can’t sleep a wink. He has been awake for 4 years 24 hours a day. His condition has baffled the parents and the doctors who have finally came after a complicated discussion to the diagnosis of this young boy as Chiari Syndrome.

When it happens it can cause headaches,vomiting, muscle weakness in the head and face, difficulty swallowing,mental impairment,paralysis of arms, paralysis of legs, progressive brain impairment, involuntary eye movements – usually rapid and downward, dizziness, double vision, deafness, impaired coordination, and in some cases death.

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23 thoughts on “10 Weirdest Medical Conditions

  1. Yay I got Aquagenic Urtikaria… That means I’m special 😀

    And we can go from a enjoy swimming etc… I don’t feel anything until after I leave the water. And its not that bad, I have no problems ignoring it.

  2. I have that one where I get itchy red spots when I take a hot shower or sweat! I’m so glad I know what it is now! It comes and goes though, it doesn’t affect me all the time.

  3. I have Alice in The Wonderland Syndrome. It is odd to have because no one understands it. I have had it my whole life, so as a child I did not know other people did not have these episodes.

  4. I don’t appreciate DID being labeled an “odd” or “rare” disorder… Its more common than people think. We have it… and we are NOT freaks! Horrible things were done to us, some lasting into adulthood, and we never asked to be like this… We weren’t given a chance to live a normal life. No medication can fix it, most don’t even effect any of the aspects or symptoms of it.

    The only way to heal is to try and intregrate, or fuse all or most of the personalities into a single persona. This doesn’t happen for most, and for the ones that manage to, its a long and hard process.

    People don’t want to believe that severe child abuse was or is this common, but it sadly is. Last i checked, up to 1% of the US’s population is thought to have it. Thats not rare enought o be considered “bizzare”, and we’re people like anyone else and should not be treated like broken goods all the time.

    A lot of cases are never even docummented. The purpose of the disorder, after all, is to maintain the illusion of a whole and functioning person, to allow the host to live and survive the awful truama without having to bear all the weight. Some don’t even knoiw they have it. We didn’t until 2 1/2 years ago.

  5. I’m 13 years old and I’ve had Alice in Wonderland’s syndrome (Todd’s syndrome) all my life, it’s such a pain! I’ve never met anyone else with it and I’m scared to tell any of my friends about it because they’ll think I’m crazy or something. When ever it actually happens, it prevents me from reading books, focusing or concentrating and watching TV because I think it makes it worse. This is like an everyday thing as well, makes it a lot worse when I’m at school 😛

  6. I have Alice in wonderland syndrome. I assume it feels like what an acid trip feels like, except the fact that it happens when you are trying to do things like have a conversation with your boss, drive home, or anything else that requires a lot of focus. For me episodes do not last long, usually 5 minutes to a few hours, but I have heard some children have it for months at a time.

    When you are in a full blown episode, you either feel way big or way small. Some times I look at my hand and feel like I am trapped in a 8 year olds body. Other episodes I feel like I am in one of those furniture stores that uses miniature display models. I end up stranded on the side of the road or just end up acting really awkward. Sometimes I can quit a trigger before it fully causes an episode and sometime I don’t know I am in one until I look around.

    Anyway, it isn’t a lot of fun when it happens but it certainly isn’t weird. In fact more and more people are coming forward saying they have it despite misdiagnosis (we thought i had strange vertigo episodes) and utter lack of recognition of symptoms by doctors.

  7. I am 27 and still have micropsia where I see little. It started when i was a toddlor. You r the first person i have seen with the alice in wonderland syndrome. I was diagnoist at age 21.

  8. actually some of them are very fortunate…the little girl with multiple limbs is considered a god in her native country, India.

  9. My brother was also a victum of recessive autosomal disorder named “Spinal muscular atrophy”. I miss u bhaiya.

  10. i have arnold chiari syndrome/malformation and i cant find a dr. to treat it in my area. i can barely walk anymore so yea it sucks

  11. Hey,qn, I also have a Chiari malformation. I had brain/spinal cord surgery in 1996. I am becoming paralyzed, suffer severe chronic pain 24/7. I’ve only met one person who has ths, so, nobody understands. When I was diagnosed we had no internet, I couldn’t find out anything about it. Now, there’s a lot of info out there. One I like, and you can get them to mail you a packet of onfo, email, chat, etc. with other Chiarians is called asap. It’s asap.com, I think. They can give you a octor list. You have to have a neurourgeon

  12. When something is described as odd or rare, it’s not an insult, it’s simply stating that it’s not something that is commonly found. The same with the term “abnormal”..it just means “not normal”..when you think of 100 people, and how they live their life, and one person is different, then technically that would be “abnormal”. It’s not a bad thing, it’s just different.

  13. My son and I have chiari malformation and him and I have meet a lot of people who have it. Its more common then people think.. you can still have it but don’t have systems (I did not get anything tell about 17 year old my son has speech delays and had troubles walking and would fall over just because.. we meet Kids from newborn toddlers & teens to adults. Each chiari person is different my son is 4 and had surgery 6 months ago and is doing great he is in karate & soccer we both suffer from bad headaches my son not as much now.. there are a lot of Facebook pages with people that have chiari. And we help everyone out or if you need that shoulder to cry on or that little push not to give up..

  14. My wife has Capgras Syndrome. I would think that should be up there as one of the weirdest medical conditions.

  15. For those with Chiari (which I have, as well), look for support groups either online or in major cities in your area. I formed a support group in my area and was shocked at the number of people I found who suffer from it, too. Check Facebook, if you are so inclined. There are tons of different groups there where people turn for support.

  16. It is ASAP.ORG and that goes hand in hand with SM: Syringomyelia; where your spinal column is filled with fluid, so that every vertebra that isn’t in perfect alignment/condition manifests in pain, malfunction, daily headaches, weakness and hopelessness that it will never be cured. Also, you can have this and look perfectly normal, temporarily. Boy oh boy, when it’s triggered, can’t walk, talk, concentrate, so weak can’t use hands, fingers, barely walk, sleep is a gift and you never know from one hour to the next, so it is very hard to live life when you can never commit to anything and if you do, you’ll probably forget about it unless you write it down. That’s my world.

  17. I suffer from chiari malformation I had decompression surgery 2 years ago and still finding it hard. For those of you with chiari and need some support or maybe to just ask a few questions there is a Facebook group set up especially for this condition it’s call ann convoy trust, ann convoy trust also has a website too . Hope this helpsx

  18. I have Cerebellar Degeneration. Can’t figure out where it came from. I have a problem with balance. I’m sure there are other symptoms that I don’t see for myself. So difficult so deal with. Doctors can’t find a cause. No cancer.

  19. I have Arnold Chiari. It’s just like described. I only sleep for a couple of hours per night. I had surgery in 2009 and it relieved many of my symptoms but it never really goes away. It’s an invisible disease in many ways and most people just don’t understand.

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